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Fertility Centre Prague, Czech Republic
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Fertility Centre Prague, Czech Republic
LABORATORY METHODS PGT-A: Preimplantation genetic testing for aneuploidies hero-image PGT-A: Preimplantation genetic testing for aneuploidies hero-image
LABORATORY METHODS

PGT-A: Preimplantation genetic testing for aneuploidies

Preimplantation genetic testing for aneuploidies (PGT-A) determines the number of chromosomes in an embryo and thus increases the chances of embryo implantation and the birth of a healthy child.

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Missing or additional chromosomes in the embryo can cause:

  • Failure to implant (nest) in the mother’s uterus.

  • Spontaneous miscarriage in the 1st trimester of pregnancy.

  • The birth of a child with, for example, Down, Edwards or Patau syndrome.

When is this method indicated? section image

When is this method indicated?

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    In case of repeated miscarriages.

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    If the mother is older.

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    If chromosomal abnormalities are found in either of the partners.

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    If the couple has repeatedly undergone unsuccessful embryo transfers in IVF cycles.

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    If sperm obtained surgically (MESA/TESA) is used.

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    Following treatment of oncological diseases associated with radiation or chemotherapy, etc.

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PGT-A preimplantation testing is most often performed on an embryo in the blastocyst stage (5th day of development) and does not affect its development. In fact, it will help infertile couples increase the success rate of transfer above 40%, even if transferring a single embryo.

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